Pharmacology:Pharmacokinetics: Indapamide is rapidly and completely absorbed from the gastro-intestinal tract. Elimination is biphasic with a half-life in whole blood of about 14 hours. Indapamide is strongly bound to red blood cells. It is extremely metabolised. About 60 to 70% of the dose has been reported to be excreted in the urine; only about 5 to 7% is excreted unchanged. About 16 to 23% of the administrated dose is excreted haemodialysis but does not accumulate in patients with impaired renal function.
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